Small/secreted glycoprotein
Seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils.
Delta-peptide
Viroporin that permeabilizes mammalian cell plasma membranes. It acts by altering permeation of ionic compounds and small molecules. This activity may lead to viral enterotoxic activity.
Pre-small/secreted glycoprotein
This precursor is processed into mature sGP and delta-peptide by host furin or furin-like proteases. The cleavage site corresponds to the furin optimal cleavage sequence [KR]-X-[KR]-R.
Small/secreted glycoprotein
N-glycosylated.
Delta-peptide
O-glycosylated.
Belongs to the filoviruses glycoprotein family.
Pre-small/secreted glycoprotein, pre-sGP, GP
Proteins
Immunology & Infectious Disease
41771Da
We found 1 product in 1 category