GP64
Function
Class III viral fusion protein. Envelope phosphoglycoprotein which mediates the fusion of viral and host endosomal membranes leading to virus entry into the host cell. After receptor-mediated internalization of the virus, gp64 undergoes conformational change into a fusion-competent state at low pH, and the nucleocapsid is released into the cytoplasm after cell fusion. May also play role in budding.
Post-translational modifications
Palmitoylated.
Sequence Similarities
Belongs to the baculoviridae gp64 family.
Cellular localization
- Virion membrane
- Single-pass membrane protein
- Host cell membrane
- Single-pass membrane protein
Alternative names
GP67, ORF128, GP64, Major envelope glycoprotein, gp64