GPD2
Function
Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.
Pathway
Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.
Sequence Similarities
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
Cellular localization
- Mitochondrion
Alternative names
GPD-M, GPDH-M, mitohondrial glycerophosphate dehydrogenase gene, mtGPD, mGDH, GPD2