Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
Belongs to the G-protein coupled receptor 1 family.
High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney.
UNQ5925/PRO19818, GPR78, G-protein coupled receptor 78
Proteins
Immuno-oncology
39332Da
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