GPR87
Function
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity
Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
GPR95, FKSG78, GPR87, G-protein coupled receptor 87, G-protein coupled receptor 95