GPRASP1
Function
Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2.
Sequence Similarities
Belongs to the GPRASP family.
Tissue Specificity
Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.
Cellular localization
- Cytoplasm
Alternative names
GASP, KIAA0443, GPRASP1, G-protein coupled receptor-associated sorting protein 1, GASP-1