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Grm7

Function

G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits (By similarity).

Sequence Similarities

Belongs to the G-protein coupled receptor 3 family.

Cellular localization

Alternative names

Gprc1g, Mglur7, Grm7, Metabotropic glutamate receptor 7, mGluR7

swissprot:Q68ED2