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Function

Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

Sequence similarities

Belongs to the chaperonin (HSP60) family.

Cellular localization

  • Cytoplasm

Alternative names

groL, mopA, c5227, groEL, Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

57329Da

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