groEL
Function
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Sequence Similarities
Belongs to the chaperonin (HSP60) family.
Cellular localization
- Cytoplasm
Alternative names
groL, mopA, c5227, groEL, Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60