Growth hormone variant
Function
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Sequence Similarities
Belongs to the somatotropin/prolactin family.
Tissue Specificity
Expressed in the placenta.
Cellular localization
- Secreted
Alternative names
Growth hormone variant, GH-V, Growth hormone 2, Placenta-specific growth hormone, GH2