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GRPEL1

Function

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (PubMed:11311562).

Sequence Similarities

Belongs to the GrpE family.

Cellular localization

Alternative names

GREPEL1, GRPEL1, HMGE, Mt-GrpE#1

swissprot:Q9HAV7 entrezGene:80273 omim:606173