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GSS
Involvement in disease
Glutathione synthetase deficiency
GSS deficiency
Severe form characterized by an increased rate of hemolysis and defective function of the central nervous system.
None
The disease is caused by variants affecting the gene represented in this entry.
Glutathione synthetase deficiency of erythrocytes
GLUSYNDE
Mild form causing hemolytic anemia.
None
The disease is caused by variants affecting the gene represented in this entry.
Pathway
Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.
Sequence similarities
Belongs to the eukaryotic GSH synthase family.
Alternative names
- Glutathione synthetase
- GSH synthetase
- GSH-S
- Glutathione synthase
- GSS
Database links
Target type
Proteins
Molecular weight
52385Da