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GSTM3

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.

Post-translational modifications

The N-terminus is blocked.

Sequence Similarities

Belongs to the GST superfamily. Mu family.

Tissue Specificity

Testis and brain.

Cellular localization

Alternative names

GST5, GSTM3, Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3

swissprot:P21266 omim:138390 entrezGene:2947