GTF3A
Function
Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes (PubMed:24120868). Also binds the transcribed 5S RNA's (By similarity).
Tissue Specificity
Ubiquitous.
Cellular localization
- Nucleus
Alternative names
Transcription factor IIIA, TFIIIA, GTF3A