Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Sequence Similarities
Belongs to the G protein gamma family.
Cellular localization
- Cell membrane
- Lipid-anchor
- Cytoplasmic side
Alternative names
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, GNG12