GUCA2A
Function
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Sequence Similarities
Belongs to the guanylin family.
Tissue Specificity
Highly expressed in ileum and colon. Found in plasma.
Cellular localization
- Secreted
Alternative names
GUCA2, GUCA2A, Guanylin, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, GCAP-I