GYPC

This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.

O-glycosylated with core 1 or possibly core 8 glycans.

Belongs to the glycophorin-C family.

Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.

• Cell membrane
• Single-pass type III membrane protein
• Linked to the membrane via band 4.1.

CD236, GLPC, GPC, GYPC, Glycophorin-C, Glycoconnectin, Glycophorin-D, Glycoprotein beta, PAS-2', Sialoglycoprotein D, GPD

• entrezGene:2995
• omim:110750
• swissprot:P04921

Proteins

Immunology & Infectious Disease

13811Da