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HECTD2

Function

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

(Microbial infection) Catalyzes ubiquitination of Botulinum neurotoxin A light chain (LC) of C.botulinum neurotoxin type A (BoNT/A).

Pathway

Protein modification; protein ubiquitination.

Alternative names

Probable E3 ubiquitin-protein ligase HECTD2, HECT domain-containing protein 2, HECT-type E3 ubiquitin transferase HECTD2, HECTD2

swissprot:Q5U5R9 entrezGene:143279