Heme oxygenase 2

Heme oxygenase 2

Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.

Heme oxygenase 2 soluble form

Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.

A soluble form arises by proteolytic removal of the membrane anchor.

S-nitrosylated by BLVRB.

Belongs to the heme oxygenase family.

Widely distributed in body with a high concentration in the brain.

• Microsome membrane
• Single-pass type IV membrane protein
• Cytoplasmic side
• Endoplasmic reticulum membrane
• Single-pass type IV membrane protein
• Cytoplasmic side

Heme oxygenase 2, HO-2, Hmox2

• entrezGene:79239
• swissprot:P23711

Proteins

Metabolism

35762Da