HERC3

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein modification; protein ubiquitination.

Ubiquitinated; which promotes degradation by the proteasome.

• Cytoplasm
• Cytoplasmic vesicle
• Also found in vesicular-like structures.

KIAA0032, HERC3, Probable E3 ubiquitin-protein ligase HERC3, HECT domain and RCC1-like domain-containing protein 3, HECT-type E3 ubiquitin transferase HERC3

• entrezGene:8916
• omim:605200
• swissprot:Q15034

Proteins

Neuroscience

117188Da