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HMGN2

Function

Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).

Post-translational modifications

Phosphorylation favors cytoplasmic localization.

Sequence Similarities

Belongs to the HMGN family.

Cellular localization

Alternative names

HMG17, HMGN2, Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2

swissprot:P05204 omim:163910 entrezGene:3151