HNRNPA0
Function
mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs.
Post-translational modifications
Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA.
Arg-291 is dimethylated, probably to asymmetric dimethylarginine.
Cellular localization
- Nucleus
- Component of ribonucleosomes.
Alternative names
HNRPA0, HNRNPA0, Heterogeneous nuclear ribonucleoprotein A0, hnRNP A0