HNRNPUL1
Domain
The RGG-box domain is methylated.
Function
Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Also plays a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
Post-translational modifications
Methylated.
Cellular localization
- Nucleus
Alternative names
E1BAP5, HNRPUL1, HNRNPUL1, Heterogeneous nuclear ribonucleoprotein U-like protein 1, Adenovirus early region 1B-associated protein 5, E1B-55 kDa-associated protein 5, E1B-AP5