Homeobox protein BarH-like 1
Function
Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.
Sequence Similarities
Belongs to the BAR homeobox family.
Tissue Specificity
Widely expressed. Expressed at higher levels in testis and heart. Detected in craniofacial tissue and adult iris, but not in lymphocytes, fibroblasts, choroid retina, retinal pigment epithelium, kidney, or fetal liver.
Cellular localization
- Nucleus
Alternative names
Homeobox protein BarH-like 1, BARX1