HOXA4
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'.
Sequence Similarities
Belongs to the Antp homeobox family. Deformed subfamily.
Tissue Specificity
Embryonic nervous system.
Cellular localization
- Nucleus
Alternative names
HOX1D, HOXA4, Homeobox protein Hox-A4, Homeobox protein Hox-1.4, Homeobox protein Hox-1D