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Function

Component of the epidermal cornified cell envelopes.

Post-translational modifications

Processed during the process of epidermal differentiation.

Forms covalent cross-links mediated by transglutaminase TGM3, between glutamine and the epsilon-amino group of lysine residues (in vitro).

Sequence similarities

Belongs to the S100-fused protein family.

In the N-terminal section; belongs to the S-100 family.

Tissue specificity

Expressed in cornified epidermis, psoriatic and regenerating skin after wounding. Found in the upper granular layer and in the entire cornified layer of epidermis.

Cellular localization

  • Cytoplasmic granule
  • Found in keratohyalin granules in the granular cells of the epidermis.

Alternative names

S100A18, HRNR, Hornerin

Target type

Proteins

Primary research area

Oncology

Molecular weight

282390Da

We found 1 product in 1 category

Primary Antibodies

Target

Reactive species

Search our catalogue for 'HRNR' (1)

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