human G-protein coupled receptor 157
Function
Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol-calcium second messenger.
Sequence Similarities
Belongs to the G-protein coupled receptor 2 family.
Cellular localization
- Cell projection
- Cilium membrane
- Multi-pass membrane protein
- Expressed in the primary cilia of radial glial progenitors (RGPs) exposed to the cerebrospinal fluid.
Alternative names
G-protein coupled receptor 157, GPR157