HYAL2
Function
Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.
Sequence Similarities
Belongs to the glycosyl hydrolase 56 family.
Tissue Specificity
Widely expressed. No expression detected in adult brain.
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
Alternative names
LUCA2, HYAL2, Hyaluronidase-2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2, LuCa-2