ICA1
Function
May play a role in neurotransmitter secretion.
Tissue Specificity
Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid.
Cellular localization
- Cytoplasm
- Cytosol
- Golgi apparatus membrane
- Peripheral membrane protein
- Cytoplasmic vesicle
- Secretory vesicle membrane
- Peripheral membrane protein
- Cytoplasmic vesicle
- Secretory vesicle
- Synaptic vesicle membrane
- Peripheral membrane protein
- Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules.
Alternative names
Islet cell autoantigen 1, 69 kDa islet cell autoantigen, Islet cell autoantigen p69, ICA69, ICAp69, p69, ICA1