ICAM4
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.
Post-translational modifications
N- and O-glycosylated.
Sequence Similarities
Belongs to the immunoglobulin superfamily. ICAM family.
Tissue Specificity
Erythrocytes.
Cellular localization
- Isoform Long
- Cell membrane
- Single-pass type I membrane protein
- Isoform Short
- Secreted
- Cell membrane
- Single-pass type I membrane protein
Alternative names
CD242, LW, ICAM4, Intercellular adhesion molecule 4, ICAM-4, Landsteiner-Wiener blood group glycoprotein, LW blood group protein