ICAM5
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
Post-translational modifications
Glycosylation at Asn-54 is critical for functional folding.
Sequence Similarities
Belongs to the immunoglobulin superfamily. ICAM family.
Tissue Specificity
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
Cellular localization
- Membrane
- Single-pass type I membrane protein
Alternative names
TLCN, TLN, ICAM5, Intercellular adhesion molecule 5, ICAM-5, Telencephalin