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Ifna11

Function

Has antiviral and antiproliferative activities (PubMed:15254193). Produced by macrophages and stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase (By similarity). During viral infection, mediates antiviral effect, either directly by inducing interferon-stimulated genes, either indirectly through stimulation of natural killer cells enabling them to control viral replication (PubMed:22912583).

Post-translational modifications

N-glycosylated (PubMed:15254193).

Sequence Similarities

Belongs to the alpha/beta interferon family.

Cellular localization

Alternative names

Interferon alpha-11, IFN-alpha-11, Limitin, Ifna11

swissprot:Q61716 entrezGene:15964