IFRD2
Function
Ribosome-binding protein that acts as an inhibitor of mRNA translation by promoting ribosome inactivation (PubMed:30355441). Associates with the P- and E-sites of the ribosome and inserts a C-terminal helix into the mRNA exit channel to preclude translation (By similarity).
Sequence Similarities
Belongs to the IFRD family.
Tissue Specificity
Expressed in many tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Alternative names
Interferon-related developmental regulator 2, Protein SKMC15, IFRD2