Skip to main content

Function

Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.

Involvement in disease

Acid-labile subunit deficiency

ACLSD

A disorder characterized by severely reduced serum IGF-I and IGFBP-3 concentrations and mild growth retardation. Pubertal delay in boys and insulin insensitivity are common findings.

None

The disease is caused by variants affecting the gene represented in this entry.

Tissue specificity

Plasma.

Cellular localization

  • Secreted
  • Extracellular space

Alternative names

ALS, IGFALS, Insulin-like growth factor-binding protein complex acid labile subunit

Target type

Proteins

Primary research area

Oncology

Molecular weight

66035Da

We found 1 product in 1 category

Proteins & Peptides

Target

Species of origin

Search our catalogue for 'IGFALS' (1)

Products