IL1RAPL2

The TIR domain mediates NAD(+) hydrolase (NADase) activity. Self-association of TIR domains is required for NADase activity.

Belongs to the interleukin-1 receptor family.

Detected at low levels in fetal and adult brain, in particular in the frontal lobe, temporal lobe and cerebellum. Detected at very low levels in skin, liver, fetal ovary and in placenta.

• Membrane
• Single-pass type I membrane protein

IL1R9, IL1RAPL2, X-linked interleukin-1 receptor accessory protein-like 2, IL-1 receptor accessory protein-like 2, IL-1-RAPL-2, IL-1RAPL-2, IL1RAPL-2, IL1RAPL-2-related protein, Interleukin-1 receptor 9, Three immunoglobulin domain-containing IL-1 receptor-related 1, IL-1R-9, IL-1R9, TIGIRR-1

• entrezGene:26280
• omim:300277
• swissprot:Q9NP60

Proteins

Immunology & Infectious Disease

78670Da