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Function

Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.

Sequence similarities

Belongs to the IL-1 family.

Cellular localization

  • Isoform 1
  • Secreted
  • Isoform 2
  • Cytoplasm

Alternative names

Il-1ra, Il1rn, Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, IL1 inhibitor

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

20274Da

We found 16 products in 4 categories

Primary Antibodies

Target

Application

Reactive species

Assay Kits

Target

Reactive species

Detection method

Proteins & Peptides

Target

Species of origin