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IL-2

Function

Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Sequence similarities

Belongs to the IL-2 family.

Cellular localization

  • Secreted

Alternative names

  • Interleukin-2
  • IL-2
  • T-cell growth factor
  • TCGF
  • Il2
  • Il-2

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Other research areas

  • Immuno-oncology

Molecular weight

19400Da