IL-3

Function

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.

This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.

Sequence similarities

Belongs to the IL-3 family.

Tissue specificity

Activated T-cells, mast cells, natural killer cells.

Cellular localization

• Secreted

Alternative names

• Interleukin-3
• IL-3
• Hematopoietic growth factor
• Mast cell growth factor
• Multipotential colony-stimulating factor
• P-cell-stimulating factor
• MCGF
• IL3

Database links

• entrezGene:3562
• omim:147740
• swissprot:P08700

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

17233Da