IL32
Function
Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.
Tissue Specificity
Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells.
Cellular localization
- Secreted
Alternative names
NK4, TAIF, IL32, Interleukin-32, IL-32, Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor