IL9R
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
Function
Plays an important role in the immune response against parasites by acting as a receptor of IL9.
Sequence Similarities
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
- Secreted
Alternative names
CD129, Interleukin-9 receptor, IL-9 receptor, IL-9R, IL9R