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Function

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.

Involvement in disease

Gilles de la Tourette syndrome

GTS

Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities.

None

The disease may be caused by variants affecting the gene represented in this entry.

Sequence similarities

Belongs to the peptidase S26 family. IMP2 subfamily.

Tissue specificity

Expressed in all tissues tested except adult liver and lung.

Cellular localization

  • Mitochondrion inner membrane
  • Single-pass membrane protein

Alternative names

Mitochondrial inner membrane protease subunit 2, IMP2-like protein, IMMP2L

Target type

Proteins

Molecular weight

19718Da

We found 1 product in 1 category

Proteins & Peptides

Target

Species of origin

Search our catalogue for 'IMMP2L' (1)

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