Ina
Developmental stage
Levels of this protein reach a maximum at embryonic day 16 and decline into adulthood.
Function
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges (By similarity). May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity).
Post-translational modifications
O-glycosylated.
Sequence Similarities
Belongs to the intermediate filament family.
Tissue Specificity
Expressed in the dorsal root ganglion neurons (at protein level).
Alternative names
Inexa, Ina, Alpha-internexin, Alpha-Inx