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ITGB1BP2

Domain

The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein.

Function

May play a role during maturation and/or organization of muscles cells.

Tissue Specificity

Expressed in skeletal and cardiac muscles but not in other tissues.

Alternative names

MSTP015, ITGB1BP2, Integrin beta-1-binding protein 2, Melusin

swissprot:Q9UKP3 entrezGene:26548 omim:300332