Involucrin

Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.

Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide.

Belongs to the involucrin family.

Keratinocytes of epidermis and other stratified squamous epithelia.

• Cytoplasm
• Constituent of the scaffolding of the cornified envelope.

Involucrin, IVL

• entrezGene:3713
• omim:147360
• swissprot:P07476

Proteins

Oncology

68479Da