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JSRP1

Function

Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity.

Cellular localization

Alternative names

JP45, JSRP1, Junctional sarcoplasmic reticulum protein 1, Junctional-face membrane protein of 45 kDa homolog, JP-45

swissprot:Q96MG2 entrezGene:126306