KAT14
Function
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.
Tissue Specificity
Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High expression in skeletal muscle and heart. Lower expression in lung.
Cellular localization
- Nucleus
- Cytoplasm
- Mainly nuclear.
Alternative names
CSRP2BP, KAT14, Cysteine-rich protein 2-binding protein, CSRP2-binding protein, ADA2A-containing complex subunit 2, CRP2-binding partner, Lysine acetyltransferase 14, ATAC2, CRP2BP