KCNJ15
Function
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Sequence Similarities
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ15 subfamily.
Cellular localization
- Membrane
- Multi-pass membrane protein
Alternative names
KCNJ14, KCNJ15, ATP-sensitive inward rectifier potassium channel 15, Inward rectifier K(+) channel Kir1.3, Inward rectifier K(+) channel Kir4.2