Kel
Function
Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3 (By similarity).
Post-translational modifications
N-glycosylated.
Sequence Similarities
Belongs to the peptidase M13 family.
Tissue Specificity
Highly expressed in spleen. Weaker expression in testis and heart.
Cellular localization
- Cell membrane
- Single-pass type II membrane protein
- Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
Alternative names
CD238, Kell blood group glycoprotein homolog, Kel