KIF21B
Function
Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.
Sequence Similarities
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Cellular localization
- Cytoplasm
- Cytoskeleton
- Cell projection
- Dendrite
- Cell projection
- Growth cone
- Cell projection
- Axon
- Cytoplasmic vesicle
Alternative names
KIAA0449, KIF21B, Kinesin-like protein KIF21B