KIF3A

Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily.

• Cytoplasm
• Cytoskeleton
• Cell projection
• Cilium
• Cytoplasm
• Cytoskeleton
• Microtubule organizing center
• Centrosome
• Centriole
• Localizes to the subdistal appendage region of the centriole.

KIF3, KIF3A, Kinesin-like protein KIF3A, Microtubule plus end-directed kinesin motor 3A

• entrezGene:11127
• omim:604683
• swissprot:Q9Y496

Proteins

Metabolism

80041Da