KIFAP3

Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex (By similarity).

Phosphorylated on tyrosine residues by SRC in vitro; this reduces the binding affinity of the protein for RAP1GDS1.

KIF3AP, SMAP, KIFAP3, Kinesin-associated protein 3, KAP-3, KAP3, Smg GDS-associated protein

• entrezGene:22920
• omim:601836
• swissprot:Q92845

Proteins

Neuroscience

91205Da